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MYP_064335
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C134H230N36O32
Standard
Sequence
GFLGPLLKLGLKGAAKLLPQLLPSRQQ
Physicochemical Analysis
2857.48 Da
11.26
3.76
3.55
0.1392
0.25
0.60
0.17
40.70
137.41
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1083.01
-6.82
35.0
36.0
96.0
202.0
4.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0170184 VERIFIED: YES
Provenance & Taxonomy
Xenopus tropicalis [Animal]
CPF
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
50.0 μM
MIC
PaperM. Mechkarska et al. / Comparative Biochemistry and Physiology, Part D 6 (2011) 206-212. Genome duplications within the Xenopodinae do not increase the multiplicity of antimicrobial peptides in Silurana paratropicalis and Xenopus andrei skin secretions
RECORD: Rec_0179441 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
50 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/22800690/ PMID22800690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800690/
RECORD: Rec_0187205 VERIFIED: YES
Provenance & Taxonomy
Silurana paratropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
6 μM
MIC
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
RECORD: Rec_0281363 VERIFIED: YES
Provenance & Taxonomy
Silurana epitropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923 and MRSA
2.5 μM
MIC
PaperHost-defense peptides in skin secretions of the tetraploid frog Silurana epitropicalis with potent activity against methicillin-resistant Staphylococcus aureus (MRSA).
RECORD: Rec_0295483 VERIFIED: YES
Provenance & Taxonomy
Silurana paratropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii
6 μM
MIC
PMID21498136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21498136/
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