Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2332H3649N617O645S12

DescriptionStandard

        TDPGFVVRITQAGLDYAHQLGIEFLEKELAQLKLQDISGDFRIRHVGKVRYEISRLELRSFHLPYSRISPVPNVGLQVSISNAFAEVDGNWRVKLYFIRDHGSFDLKVENVYIKISLKLGSDSSGKPTIDTSDCNTRISRVWVHFSGKLAWLYNLFYGAIEARFRKLLENKVCESVASNVRQQLQPYARTLPVTARIDAMAGIDYSLVAPPTATAQSLDVDLKGEFFSMAHRSAIPFLPLPLAFPPDHDRMVYFGASSYFFNTAAFTYHRAGALVFELTDSMIPKSMDFHLNTSTFSAFIPQLEKKYPETPMKLMLSTPTAPFLSIGPGAFSLRPVVDIQAYAILPNSSLAPLFLLSLVSNVSAVINVKSGHIVGSLDVGRMKLSLKQSDVGTFQVRMLQSIMNIFASNILLPRLNARLDEGFPLPLPDKIQLSNILVRFHQNFLLLGADVRYQPR
    

Molecular Weight51033.44 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)8.37

Net Charge (pH 7.4) 7.50

Charge Density (pH 7.0) 0.0184

GRAVY Index0.06

Hydrophobic Moment 0.70

Boman Index0.10

Instability Index34.47

Aliphatic Index 100.29

Aromaticity 0.1053

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 38975.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0181472 VERIFIED: NO

Provenance & Taxonomy

OrganismUpupa epops [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria