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MYP_064324
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Basic Information
Oncocin [R19N]
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
19 amino acids
C107H170N34O26
Standard
Sequence
VDKPPYLPRPRPPRRIYNN
Physicochemical Analysis
2348.71 Da
10.93
3.73
3.52
0.1964
-1.69
0.51
-0.49
62.05
56.32
0.1053
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
971.94
-7.79
32.0
30.0
66.0
167.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0348942 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus ATCC 10240
64 μg/mL
MIC
Mouse serum: The half-life is 120 min in 25% aqueous mouse serum
PaperKnappe D, Kabankov N, Hoffmann R Bactericidal oncocin derivatives with superior serum stabilities Int J Antimicrob Agents. 2011 Feb;37(2):166-70. PMID:21185160 https://pubmed.ncbi.nlm.nih.gov/21185160/ PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
RECORD: Rec_0401287 VERIFIED: YES
Provenance & Taxonomy
Oncopeltus [Animal]
Oncocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Nmr =N-methylarginine
Bio-Activity Profile
Antimicrobial
8 μg/mL
MIC
25% mouse serum, in vivo; 4740 s
PaperBactericidal oncocin derivatives with superior serum stabilities PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
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