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MYP_064277
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Basic Information
T-20S[138A]
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
36 amino acids
C202H298N50O63
Standard
Sequence
YTSLIHSLIEEAQNQQEKNEQELLELDKWASLWNWF
Physicochemical Analysis
4434.82 Da
4.30
-5.14
-5.41
-0.1427
-0.80
0.51
-0.02
51.95
92.22
0.1389
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1873.79
-13.93
62.0
59.0
149.0
315.0
9.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0160400 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 NL4-3 N43D/S138A
PMID19073606 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19073606/
RECORD: Rec_0162753 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1V38A:inhibition of virus replication in HeLa cells
0.0036±0.0017 μM
EC50
PaperDesign of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20 PMID19073606 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19073606/
RECORD: Rec_0179653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID19073606 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19073606/
RECORD: Rec_0191763 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1WT:inhibition of virus replication in HeLa cells
0.0006±0.0001 μM
EC50
PaperDesign of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20 PMID19073606 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19073606/
RECORD: Rec_0220726 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 NL4-3 N43D
PMID19073606 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19073606/
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