Peptide Database

Peptide NameVgrG protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1196 amino acids

Chemical FormulaC5873H9116N1670O1809S30

DescriptionStandard

        MDNWSALFDGQTRYFLDINDSSVQPDVLRFYGREALSEPFNWDIEFTSPEANILPEEVLMKYASFRMRSGKSVHGRVTRLEWLSTSRDQSHYRLTLSSRLALLEYARQCAVYQNQSVPEVVEQVLRKHGLEGPDFEFRLERTYPPREIITQWRETDLQFIRRILSEVGIYWRTEMDDVRGLDTYIFADSQLNYRFDVRLPYSEPSGLFDGAAESVWDVRTWHNIATGTVTSRDYNYRTASTPMDATVSVRSDAVTTGKHYRYAAPYRDAGDDTSPEPETESGAFYARIHHERELNKSSRIHLFSNASGLTPGQVLETQGNVIAALQEGVVLTLVTFRGARDSRLHVSVWGLPYTERYCFRPAEIPRPEIHGTLPARIESREKNDTYAHLDEQGRYRVKPDFDREGTEPGYGYLWLRMAKPYAGETLGWHTPLIDGAEVAIAYSNGDIDLPYIACALHDSEHPDLVNRENHTRNVLRTPANNKLRMEDRRGEEHIKLATEYGKTQLNSGHLVDAQGQRRGQGSELRTDEWGILRAGKGLFVAADAQAKAQGDALDRDAALKEIDRLNQQLQLLEMAAEQAQALKADVDSQIQMFEQRLKPLNEAVLFSAPEGMALTSGEDMQLAAGRNLAVNAGGDISVGVMGNATIFTGEKLGLFARTGQLSLKSGEGPVEVQAQNANMRLFAQKKLTLSSASDISFVGKKRITLIGGGSYLRLEAGKVEYGTTASYMRKVKRTMAASASAKPAQAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHEHEHADDEVVQHAQSAKKRKPDAGGASAPAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKAITGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSEHNQYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIKPIDQATILVTPIPDGKDEYTTPPFPVPDERDLNDYILVFPADSGIKPIYVYLKDDLRNQAGTATGNGAQIENGKLWLDLSVTNSGEGAKIPAHIADKLRGRKYKDFREFREDLWLEISKDPELSKQFSQSNIAAMGKGNAPTGSSAGFYQGPNRLVKKFEIHHNKPIEEGGGVYDIDNLRITTPKQHKFIHYGK
    

Molecular Weight133023.26 Da

Isoelectric Point (pI)5.63

Net Charge (pH 7.0)-25.72

Net Charge (pH 7.4) -27.90

Charge Density (pH 7.0) -0.0215

GRAVY Index-0.55

Hydrophobic Moment 0.79

Boman Index-0.05

Instability Index36.63

Aliphatic Index 73.22

Aromaticity 0.0878

Extinction Coeff. Reduced 178540.00

Extinction Coeff. Oxidized 178915.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0074392 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica I [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli

MethodQualitative functional evidence