Peptide Database

Peptide NameSperm-associated antigen 11A (Antimicrobial-like protein Bin-1b) (Human epididymis-specific protein 2) (He2) (Protein EP2) (Sperm antigen HE2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC626H974N186O165S3

DescriptionStandard

        MRQRLLPSVTSLLLVALLFPGSSQARHVNHSATEALGELRERAPGQGTNGFQLLRHAVKRDLLPPRTPPYQVHISHQEARGPSFKICVGFLGPRWARGCSTGNEKYHLPYAARDLQTFFLPFW
    

Molecular Weight13841.77 Da

Isoelectric Point (pI)10.54

Net Charge (pH 7.0)8.01

Net Charge (pH 7.4) 7.45

Charge Density (pH 7.0) 0.0652

GRAVY Index-0.32

Hydrophobic Moment 0.65

Boman Index-0.01

Instability Index44.38

Aliphatic Index 82.52

Aromaticity 0.0976

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5577.26

LogP -52.64

H-bond Donors 196.0

H-bond Acceptors 182.0

Rotatable Bonds 439.0

Heavy Atoms 980.0

Ring Count 31.0

Amide Bonds 132.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370710 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilySPAG11

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)