Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC315H511N81O92S10

DescriptionStandard

        MKPLVIVLVLLSHVDPALAGLNPLSSEMHQKCYGNGICRLECSTSEMLVAYCMFQLECCVKGNPEP
    

Molecular Weight7225.56 Da

Isoelectric Point (pI)5.46

Net Charge (pH 7.0)-2.37

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0360

GRAVY Index0.38

Hydrophobic Moment 0.52

Boman Index0.19

Instability Index38.14

Aliphatic Index 101.82

Aromaticity 0.0455

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2709.28

LogP -22.87

H-bond Donors 95.0

H-bond Acceptors 102.0

Rotatable Bonds 235.0

Heavy Atoms 498.0

Ring Count 10.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0073258 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Tax ID9685

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence