Peptide Database

Peptide NameGranulysin (Lymphokine LAG-2) (Protein NKG5) (T-cell activation protein 519)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC707H1165N215O209S11

DescriptionStandard

        MATWALLLLAAMLLGNPGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRLCIPSTGPL
    

Molecular Weight16373.84 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)7.54

Net Charge (pH 7.4) 7.14

Charge Density (pH 7.0) 0.0520

GRAVY Index-0.36

Hydrophobic Moment 0.86

Boman Index-0.12

Instability Index45.54

Aliphatic Index 85.45

Aromaticity 0.0552

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6903.54

LogP -73.32

H-bond Donors 252.0

H-bond Acceptors 229.0

Rotatable Bonds 548.0

Heavy Atoms 1142.0

Ring Count 18.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010875 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Antiparasitic Anti-tuberculosis Anti-Gram-positive Non-hemolytic

TargetMycobacterium (Gram-positive)