Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC359H568N104O87S7

DescriptionStandard

        MKIHLFFFILLFWATILPAKKKYPQYGSLDLRRECRKGNGRCRVECHESEIRIAFCIRPGSHCCLQK
    

Molecular Weight7957.45 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)7.71

Net Charge (pH 7.4) 7.23

Charge Density (pH 7.0) 0.1150

GRAVY Index-0.17

Hydrophobic Moment 0.59

Boman Index-0.06

Instability Index65.87

Aliphatic Index 84.48

Aromaticity 0.1194

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3085.95

LogP -21.87

H-bond Donors 116.0

H-bond Acceptors 105.0

Rotatable Bonds 266.0

Heavy Atoms 557.0

Ring Count 15.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033477 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence

RECORD: Rec_0400731 VERIFIED: NO

Provenance & Taxonomy

OrganismEnhydra lutris kenyoni [Bacterium]

FamilyDefensin

Tax ID391180

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence