‹ ›
MYP_064183
← PREVIOUS NEXT → BACK
Basic Information
Gramicidin A
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Reproductive biology ▸ Contraceptive activity ▸ Spermicidal
Wound healing/Regeneration ▸ Wound healing
Standard
15 amino acids
C96H135N19O16
Standard
Sequence
VGALAVVVWLWLWLW
Physicochemical Analysis
1811.22 Da
5.50
-0.27
-0.48
-0.0177
2.11
0.08
0.90
70.05
194.67
0.2667
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
533.88
5.56
20.0
16.0
49.0
131.0
8.0
14.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0273264 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Peptide antibiotic
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Formylation
Hydroxyethyl amide
Four tryptophans of gramicidin A modified with formic acid
Bio-Activity Profile
Antimicrobial Antibiotic Antiparasitic Antimalarial
Plasmodium berghei
0.067 μM
Percent inhibition; Microscopy (Giemsa staining)
PMID9257760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9257760/
RECORD: Rec_0276772 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 86.7%, T 0.0%, C 13.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0309310 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0331736 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://patents.google.com/patent/US7078380B2/en PatentUS 7078380 B2
RECORD: Rec_0363362 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Peptide antibiotic
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Formylation
Hydroxyethyl amide
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium chabaudi
1.4 mg/kg
ED50; Microscopy (Giemsa staining)
PMID9055986 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9055986/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 3 of 4