Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC392H634N110O106S10

DescriptionStandard

        MKFLFLFLVILLATEPMVSAECWMDGKCRLVCKNDEDSVIRCANRKRCCVPSRYLTVKPMTVERVEPWTVPHTRNQ
    

Molecular Weight8904.55 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)3.54

Net Charge (pH 7.4) 3.17

Charge Density (pH 7.0) 0.0466

GRAVY Index-0.05

Hydrophobic Moment 0.61

Boman Index-0.04

Instability Index41.96

Aliphatic Index 84.47

Aromaticity 0.0789

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3478.36

LogP -28.01

H-bond Donors 128.0

H-bond Acceptors 121.0

Rotatable Bonds 291.0

Heavy Atoms 618.0

Ring Count 14.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038846 VERIFIED: NO

Provenance & Taxonomy

OrganismEnhydra lutris kenyoni [Bacterium]

FamilyDefensin

Tax ID391180

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence