Peptide Database

Peptide NameCecropin-B [F5L,I8K,E9I,G12L,I15R,R16I,L29K,G30L,E31Q,K33L]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC185H332N54O39S

DescriptionStandard

        KWKVLKKKIKMLRNRINGLVKAGPALKVKLQALAL
    

Molecular Weight3969.02 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)10.75

Net Charge (pH 7.4) 10.53

Charge Density (pH 7.0) 0.3072

GRAVY Index-0.02

Hydrophobic Moment 0.67

Boman Index-0.07

Instability Index19.95

Aliphatic Index 136.57

Aromaticity 0.0286

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1546.97

LogP -7.71

H-bond Donors 54.0

H-bond Acceptors 51.0

Rotatable Bonds 145.0

Heavy Atoms 279.0

Ring Count 3.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383177 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman erythrocytes

Activity>250 μM

MethodHemolysis

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