MYP_064095
Pagoamide A
Antimicrobial
Standard
11 amino acids
C49H73N11O15S2
Standard
VCGCSTSAFVF
1120.30 Da
5.48
-0.29
-0.53
-0.0260
1.65
0.06
0.53
9.09
61.82
0.1818
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
415.01
-5.08
17.0
17.0
32.0
77.0
2.0
10.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0195726
VERIFIED: YES
Provenance & Taxonomy
Derbesia sp [Protist]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Esterification
Warning: Pagoamide A contains non-standard amino acids: (1) N-terminal valine is dimethylated, (2) three D-amino acids are A8, F9, and V10. This peptide, and (3) residues V1 and C2, as well as residues G3 and C4 are fused to thiazoles. Finally, the hydroxyl group of T6 and the C-terminal carboxylic group of F11 forms an ester bond, leading to a sidechain-backbone cyclized peptide
Bio-Activity Profile
Antimicrobial
Bacillus subtilis BCRC 10614
64 μg/mL
MIC