Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC726H1135N213O203S5

DescriptionStandard

        MAKVQFKPRHATDFIVVHCAATKPTMDIGVREIRQWHVQQGWLDVGYHFVIRRNGTVEDGRPHDVIGSHVKNYNSRSLGICLAGGIDAKGNPENNFTPEQFASLKLLLIATKRQYPQAQIVGHHDLDAGKACPSFKVSDWLKTAGI
    

Molecular Weight16255.41 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.18

Net Charge (pH 7.4) 4.48

Charge Density (pH 7.0) 0.0355

GRAVY Index-0.33

Hydrophobic Moment 0.68

Boman Index0.01

Instability Index31.30

Aliphatic Index 82.81

Aromaticity 0.0822

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6665.34

LogP -64.95

H-bond Donors 231.0

H-bond Acceptors 221.0

Rotatable Bonds 534.0

Heavy Atoms 1147.0

Ring Count 30.0

Amide Bonds 159.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194587 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas phage Waldo5 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic