Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length473 amino acids

Chemical FormulaC2346H3715N595O694S21

DescriptionStandard

        MRKMLSICCSLLLLSLHSGELCANPGLKVRITQKGLEYAKEVGLEILKQNMEKEGFPDLTGHERFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLMIGNASLTIDMNWSLRTWMFKDSGRGTVHISKVFVTAMLSTPLDDTGHTSISLTSCRTTSGDVDIKLNGKTGFLHNFFIKYLKKPIHRSLVTNSCPNIRAGIQLIDEDLRSLNAVMQIDDLAEVDYSLSSLPAVFQPFIDLDLKGAVFPAGNYSDSPYKAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMSAEIPVISLQQDSFTLEIQGSMEVLAVLPDSTTQSLLTLSIAANTSISLNIFNKKLMGSLCLNRIQFSLAHSNVGSFEVLPLENILSYILQTEVIPSANAKLSKGFPLPNLANVTLTRPHITIVQGYVLISTDVHYKH
    

Molecular Weight52032.53 Da

Isoelectric Point (pI)6.13

Net Charge (pH 7.0)-4.57

Net Charge (pH 7.4) -5.55

Charge Density (pH 7.0) -0.0097

GRAVY Index0.16

Hydrophobic Moment 0.77

Boman Index0.16

Instability Index35.70

Aliphatic Index 102.45

Aromaticity 0.0867

Extinction Coeff. Reduced 34840.00

Extinction Coeff. Oxidized 35215.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147293 VERIFIED: NO

Provenance & Taxonomy

OrganismCyanoderma ruficeps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria