Peptide Database

Peptide NameHepcidin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC436H686N124O126S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFTGQVQEPEEAGSNDTPVVAHQEMSMESWMMPNHIRQKRQSHLSLCRWCCNCCRGNKGCGFCCKF
    

Molecular Weight10129.78 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0075

GRAVY Index0.08

Hydrophobic Moment 0.66

Boman Index0.08

Instability Index66.46

Aliphatic Index 68.57

Aromaticity 0.0769

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3987.90

LogP -41.81

H-bond Donors 145.0

H-bond Acceptors 144.0

Rotatable Bonds 332.0

Heavy Atoms 700.0

Ring Count 16.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172089 VERIFIED: NO

Provenance & Taxonomy

OrganismChelon ramada [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal