Peptide Database

Peptide NameA-12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC84H144N26O15

DescriptionStandard

        KLKKLLKHLHHLLH
    

Molecular Weight1758.21 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)4.10

Net Charge (pH 7.4) 3.69

Charge Density (pH 7.0) 0.2932

GRAVY Index-0.40

Hydrophobic Moment 0.71

Boman Index-0.09

Instability Index-14.97

Aliphatic Index 167.14

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 660.42

LogP -0.64

H-bond Donors 23.0

H-bond Acceptors 23.0

Rotatable Bonds 63.0

Heavy Atoms 125.0

Ring Count 4.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022179 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStreptococcus mutans

Activity8 μg/mL

MethodMIC

RECORD: Rec_0294574 VERIFIED: NO