Peptide Database

Peptide NameNigrocin-2L

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC88H159N23O24S3

DescriptionStandard

        GILSGILGMGKKLVCGLSGLC
    

Molecular Weight2019.54 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0828

GRAVY Index1.30

Hydrophobic Moment 0.46

Boman Index0.47

Instability Index11.70

Aliphatic Index 143.81

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 737.82

LogP -6.28

H-bond Donors 28.0

H-bond Acceptors 29.0

Rotatable Bonds 71.0

Heavy Atoms 138.0

Ring Count 0.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0380242 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana livida [Animal]

FamilyNigrocin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide15-21

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity15 μM

MethodMIC

FIRST PREV 1 2 3

Showing 1 records on this page Ã‚Â· Page 3 of 3