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MYP_064053
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Basic Information
Nigrocin-2L
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
21 amino acids
C88H159N23O24S3
Standard
Sequence
GILSGILGMGKKLVCGLSGLC
Physicochemical Analysis
2019.54 Da
8.90
1.74
1.50
0.0828
1.30
0.46
0.47
11.70
143.81
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
737.82
-6.28
28.0
29.0
71.0
138.0
0.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0064318 VERIFIED: YES
Provenance & Taxonomy
Odorrana livida [Animal]
Nigrocin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
50.0 μM
MIC
PaperL. Wang et al. / FEBS Journal 277 (2010) 1519-1531. Nigrocin-2 peptides from Chinese Odorrana frogs - integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis Evidence URLhttps://www.uniprot.org/uniprotkb/A1JUI7/entry
RECORD: Rec_0107475 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20308076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20308076/
RECORD: Rec_0138924 VERIFIED: YES
Provenance & Taxonomy
Odorrana livida [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial
Escherichia coli
15 μM
MIC
PaperNigrocin-2 peptides from Chinese Odorrana frogs--integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis
RECORD: Rec_0171031 VERIFIED: YES
Provenance & Taxonomy
Odorrana livida [Animal]
Nigrocin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
15.0 μM
MIC
PaperL. Wang et al. / FEBS Journal 277 (2010) 1519-1531. Nigrocin-2 peptides from Chinese Odorrana frogs - integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis Evidence URLhttps://www.uniprot.org/uniprotkb/A1JUI7/entry
RECORD: Rec_0172278 VERIFIED: YES
Provenance & Taxonomy
Odorrana livida [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20158520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20158520/
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