Peptide Database

Peptide NameVpr 9-23

Function Ontology

Antimicrobial

Antiviral

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Reverse transcriptase inhibition

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC84H125N21O26

DescriptionStandard

        GPQREPYNEWTLELL
    

Molecular Weight1845.02 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.1488

GRAVY Index-1.14

Hydrophobic Moment 0.29

Boman Index-0.10

Instability Index14.97

Aliphatic Index 78.00

Aromaticity 0.1333

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 769.37

LogP -4.98

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 56.0

Heavy Atoms 131.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0331038 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Reverse transcriptase inhibition Integrase inhibition

MethodQualitative inhibition

RECORD: Rec_0385951 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 13.3%, T 46.7%, C 40.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial