Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC531H883N133O143S3

DescriptionStandard

        MAPLAPLFILILDTSVSARAYITGVKLAGTVALNRIGLTVGTSYVGPFQVKSLENILLLVLKVAVIPQVNVRLQQGFPLPTLGKMNLVNPQLQVQKDYMLIGTDVTL
    

Molecular Weight11514.69 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.27

Charge Density (pH 7.0) 0.0327

GRAVY Index0.68

Hydrophobic Moment 0.47

Boman Index0.29

Instability Index34.89

Aliphatic Index 139.25

Aromaticity 0.0561

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4371.92

LogP -32.29

H-bond Donors 146.0

H-bond Acceptors 150.0

Rotatable Bonds 377.0

Heavy Atoms 810.0

Ring Count 13.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399585 VERIFIED: YES

Provenance & Taxonomy

OrganismAnguilla anguilla [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria