Peptide Database

Peptide NameLantibiotic Flvbeta.e

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC335H534N86O110S7

DescriptionStandard

        MNNKEFNMEQFKKLAAVVSEDELDEMLDENVTGAASSIPCAKVVVKVTTVVVAATTGFDWCPTGACTTSCRF
    

Molecular Weight7750.79 Da

Isoelectric Point (pI)4.50

Net Charge (pH 7.0)-4.52

Net Charge (pH 7.4) -4.82

Charge Density (pH 7.0) -0.0628

GRAVY Index0.12

Hydrophobic Moment 0.47

Boman Index0.10

Instability Index26.62

Aliphatic Index 73.06

Aromaticity 0.0694

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3150.84

LogP -34.92

H-bond Donors 111.0

H-bond Acceptors 113.0

Rotatable Bonds 255.0

Heavy Atoms 538.0

Ring Count 8.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339276 VERIFIED: YES

Provenance & Taxonomy

OrganismRuminococcus flavefaciens [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Synergistic peptide Non-hemolytic

TargetGram-positive bacteria