Peptide Database

Peptide Namedelta-Conotoxin GmVIA

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC145H228N42O38S6

DescriptionStandard

        VKPCRKEGQLCDPIFQNCCRGWNCVLFCV
    

Molecular Weight3360.01 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.37

Charge Density (pH 7.0) 0.0578

GRAVY Index0.09

Hydrophobic Moment 0.61

Boman Index-0.00

Instability Index8.50

Aliphatic Index 70.34

Aromaticity 0.1034

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1299.13

LogP -11.45

H-bond Donors 49.0

H-bond Acceptors 46.0

Rotatable Bonds 107.0

Heavy Atoms 231.0

Ring Count 6.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291615 VERIFIED: NO

Provenance & Taxonomy

OrganismConus gloriamaris [Animal]

FamilyConotoxin

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-29, 11-24, 18-28

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0362073 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 31.0%, E 0.0%, T 48.3%, C 20.7% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic