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MYP_063975
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Basic Information
gB122Δ13-15
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
12 amino acids
C66H88N20O16
Standard
Sequence
GHRRYFTFGGGY
Physicochemical Analysis
1417.53 Da
9.99
1.85
1.59
0.1538
-0.96
0.34
-0.06
74.39
0.00
0.3333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
596.59
-5.49
23.0
19.0
42.0
102.0
5.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0069982 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
Herpes simplex virus type 1 (HSV-1)
91.4±9.8 μM
EC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperMultiple peptides homologous to herpes simplex virus type 1 glycoprotein B inhibit viral infection. | Akkarawongsa R, Pocaro NE, Case G, Kolb AW, Brandt CR. | Antimicrob Agents Chemother. 2009 Mar;53(3):987-96. | DOI:10.1128/AAC.00793-08 | PMID:19104014 PMID19104014 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19104014/
RECORD: Rec_0275968 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 19104014 PMID19104014 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19104014/
RECORD: Rec_0334143 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus type 1(HSV-1):comprehensive antiviral activity
91.4±9.8 μM
EC50
PaperPubMed PMID: 19104014 PMID19104014 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19104014/