MYP_063924
17BIPHE2
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
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Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antiviral
▸
Anti-Filovirus
▸
Antiviral
▸
Antiviral mechanism
▸
Toxicity / Safety
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Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
not Standard
17 amino acids
-
contains X representing unresolved or non-standard residue
GXKRLVQRLKDXLRNLV
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0041715
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
biphenylalanines at 2,12; biphenylalanines
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Escherichia coli E423-17
4 μM
MIC
RECORD: Rec_0049976
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
The 'X' at position 2 and 12 indicates biphenylalanine
Bio-Activity Profile
Antimicrobial
inhibition of viral infection in primary macrophages
5.6 μM
IC50
RECORD: Rec_0081071
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
biphenylalanines at 2,12; biphenylalanines
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Klebsiella pneumoniae E406-17
4-8 μM
MIC
RECORD: Rec_0089370
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
biphenylalanines at 2,12; biphenylalanines
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Pseudomonas aeruginosa E411-17
8 μM
MIC
RECORD: Rec_0104191
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L. at 2,12; biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L.
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Klebsiella pneumoniae
3.1 μM
MIC
Showing 5 records on this page · Page 1 of 5