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MYP_063898
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Basic Information
IL-4RaÐlytic hybrid peptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
33 amino acids
C184H338N54O38
Standard
Sequence
KQLIRFLKRLDRNGGGKLLLKLLKKLLKLLKKK
Physicochemical Analysis
3914.99 Da
11.80
11.75
11.53
0.3561
-0.34
0.99
-0.25
5.39
153.64
0.0303
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1563.90
-6.66
56.0
50.0
152.0
276.0
1.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153387 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
IL-4R-targeting peptide
9606
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
H-322
3.6 μM
IC50
PMID22084165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22084165/
RECORD: Rec_0180336 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
IL-4R-targeting peptide
9606
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
SU.86.86
7.5 μM
IC50
PMID22084165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22084165/
RECORD: Rec_0235917 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
Evidence URLhttps://patents.google.com/patent/US20110319336A1/en PatentUS 2011/0319336 A1
RECORD: Rec_0261434 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
IL-4R-targeting peptide
9606
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
T98G
18.5 μM
IC50
PMID22084165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22084165/
RECORD: Rec_0281306 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactoferrin-derived peptide
9913
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
KB
13.2 μM
IC50
PMID22084165 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22084165/
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