Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length541 amino acids

Chemical FormulaC2675H4238N764O729S18

DescriptionStandard

        MGDVPVQPARPPQDGHWRHRSLLPAATHKESGPTMGPAAPVGHAPRPCRCPGASGSLPTRVHLLSGATLGMWLCLLLLMAVCVPASASSPGIKGRVTRSALEYGRRFGLDLLRSLLQKEHDLNLQGSYQTPFLGRLNYTVPQIHIHELQMNDSTVDFAEDVGVQLTVHRAQIQLSATWRAQLGAWRDSGSLRLHIGDLAVAVLLGLGADEQGQPSMWAAGCDAHGTDLHLEFHRGQSWLYNLLVPLLQRTLRQQLNKKLCVEIQKGIGRLQDSLKNVRVSAQLDPFAAIDLSLLGQPAITKQHGDVDLKGEFFGVHGRWQSPFSAQPVKLPELEEPMLLVAVTEFVANTAAFVYFTAGALRRNITAEMLPRRFPLKLNTESMGNFAPQLQQHFPSRPVELHLWARRQPLLSCHPNALHGALFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTIAGNRLGGTVGLKSLSVVQVMSYVGPLQVEKLENTLKFGLWLFGVPWANKRLRPGIPLPTPHGITLLHPRLSLHKGFMLITTDLHYKP
    

Molecular Weight59342.12 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)15.49

Net Charge (pH 7.4) 13.92

Charge Density (pH 7.0) 0.0286

GRAVY Index-0.05

Hydrophobic Moment 0.79

Boman Index0.09

Instability Index51.09

Aliphatic Index 98.26

Aromaticity 0.0684

Extinction Coeff. Reduced 65430.00

Extinction Coeff. Oxidized 65805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372527 VERIFIED: NO

Provenance & Taxonomy

OrganismChrysolophus pictus (Golden pheasant) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria