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MYP_063858
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Basic Information
Defensin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
43 amino acids
C203H323N63O56S6
Standard
Sequence
ATCDILSFQSQWVTPNHAGCALHCVIKGYKGGQCKITVCHCRR
Physicochemical Analysis
4734.51 Da
8.92
4.00
3.56
0.0929
0.00
0.45
0.04
39.87
72.56
0.0698
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1911.46
-21.37
73.0
69.0
153.0
328.0
8.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0254019 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
PaperPubMed PMID: 8002963 PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
RECORD: Rec_0258441 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli D22
2.5-5 μM
MIC
PaperNovel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus
RECORD: Rec_0283345 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli D22
PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
RECORD: Rec_0322939 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Escherichia coli D22
PaperPubMed PMID: 8002963 PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
RECORD: Rec_0341521 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperBiochem J. 1994 Jun 1;300 ( Pt 2):567-75. | http://www.ncbi.nlm.nih.gov/pubmed/8002963 PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
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