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MYP_063858
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Basic Information
Defensin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
43 amino acids
C203H323N63O56S6
Standard
Sequence
ATCDILSFQSQWVTPNHAGCALHCVIKGYKGGQCKITVCHCRR
Physicochemical Analysis
4734.51 Da
8.92
4.00
3.56
0.0929
0.00
0.45
0.04
39.87
72.56
0.0698
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1911.46
-21.37
73.0
69.0
153.0
328.0
8.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019863 VERIFIED: NO
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal
A.viridans, Bacillus megaterium, Bacillus subtilis, Micrococcus luteus, P.acidilactici, Staphylococcus aureus
Qualitative functional evidence
PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/; https://www.uniprot.org/uniprotkb/P37364/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0035618 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
A. viridans
0.3-0.6 μM
MIC
PaperNovel inducible antibacterial peptides from a hemipteran insect, the sap-sucking bug Pyrrhocoris apterus
RECORD: Rec_0058001 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
saprophyticus
PaperPubMed PMID: 8002963 PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
RECORD: Rec_0071379 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPubMed PMID: 8002963 PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
RECORD: Rec_0072183 VERIFIED: YES
Provenance & Taxonomy
Pyrrhocoris apterus [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
PaperPubMed PMID: 8002963 PMID8002963 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8002963/
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