Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC315H521N97O86S7

DescriptionStandard

        LGAAEGHCLSLSGVCRRDVCKVVEDQIGACRRRRKCCRAWWILTPIPTPLNMSDYQEPLKPKLK
    

Molecular Weight7267.56 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.0905

GRAVY Index-0.33

Hydrophobic Moment 0.66

Boman Index-0.13

Instability Index64.83

Aliphatic Index 85.31

Aromaticity 0.0469

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2950.78

LogP -27.49

H-bond Donors 110.0

H-bond Acceptors 100.0

Rotatable Bonds 239.0

Heavy Atoms 505.0

Ring Count 11.0

Amide Bonds 66.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0337880 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence