Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1143H1746N266O345S8

DescriptionStandard

        IDDLAEVDYSLNSSPAVFRRFIDLDLKGIVHPAGNYTGTPCVAAPLAIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLVATEIPVISLEQDSFTAEIQGSMEVFAVLPDSTTQSLFTMNIAANTSFALNIFDQKLMGSLCLNRLQFSLAHSNVGFFETSLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight24990.18 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-14.06

Net Charge (pH 7.4) -14.46

Charge Density (pH 7.0) -0.0617

GRAVY Index0.32

Hydrophobic Moment 0.65

Boman Index0.24

Instability Index46.17

Aliphatic Index 97.59

Aromaticity 0.1228

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172844 VERIFIED: YES

Provenance & Taxonomy

OrganismOpisthocomus hoazin [Animal]

FamilyBPI/LBP

Tax ID30419

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria