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MYP_063803
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Basic Information
Dermaseptin S4 (1-16)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C85H149N21O18S
Standard
Sequence
ALWMTLLKKVLKAAAK
Physicochemical Analysis
1785.29 Da
10.48
3.79
3.60
0.2370
0.71
0.70
0.20
21.26
140.62
0.0625
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
639.92
-1.04
23.0
23.0
62.0
125.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0118302 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Escherichia coli TG1
20
IC50
PMID29439871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29439871/
RECORD: Rec_0239611 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
23±1 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/10660589/ PMID10660589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10660589/
RECORD: Rec_0240710 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Baby Hamster Kidney cells BHK-21 BSR 10% Cytotoxicity at 10 microM
21 μM
Hemolysis
PMID29439871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29439871/
RECORD: Rec_0302613 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0307047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Rabies virus RABV
PMID29439871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29439871/