Peptide Database

Peptide NameSLAY-screened peptide P691

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC111H164N30O29

DescriptionStandard

        HETPYHHRALAPVPASLLFPE
    

Molecular Weight2382.67 Da

Isoelectric Point (pI)6.28

Net Charge (pH 7.0)-0.97

Net Charge (pH 7.4) -1.33

Charge Density (pH 7.0) -0.0461

GRAVY Index-0.31

Hydrophobic Moment 0.42

Boman Index0.12

Instability Index69.53

Aliphatic Index 83.81

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 893.39

LogP -5.57

H-bond Donors 29.0

H-bond Acceptors 31.0

Rotatable Bonds 66.0

Heavy Atoms 170.0

Ring Count 9.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118961 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/