Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC332H519N97O105S2

DescriptionStandard

        QHWSYGLSPGGKRQLDSLSQTLGNVVEEFPRVDSPCSVLGGAEESPFAGIYRMKGFLGSITDRGNRTQNI
    

Molecular Weight7613.39 Da

Isoelectric Point (pI)6.77

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.43

Charge Density (pH 7.0) -0.0022

GRAVY Index-0.51

Hydrophobic Moment 0.72

Boman Index-0.03

Instability Index52.74

Aliphatic Index 69.57

Aromaticity 0.0857

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3267.79

LogP -39.51

H-bond Donors 114.0

H-bond Acceptors 108.0

Rotatable Bonds 250.0

Heavy Atoms 536.0

Ring Count 12.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211257 VERIFIED: YES

Provenance & Taxonomy

OrganismVerasper moseri [Animal]

FamilyProgonadoliberin

Tax ID98923

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour