Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC553H870N144O168S4

DescriptionStandard

        PDLSGYEKYGLGNVKYNISRIHVTAVEFPSASISFIPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGKSTVYISKVFVTAIFSTPPDNTGHTSMSLTGCRTTSGDIDIKLNGKS
    

Molecular Weight12351.95 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.92

Charge Density (pH 7.0) 0.0274

GRAVY Index-0.06

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index11.34

Aliphatic Index 82.89

Aromaticity 0.0965

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4992.20

LogP -55.36

H-bond Donors 178.0

H-bond Acceptors 177.0

Rotatable Bonds 404.0

Heavy Atoms 869.0

Ring Count 20.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346941 VERIFIED: NO

Provenance & Taxonomy

OrganismChionis minor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria