Peptide Database

Peptide NameAngiotensin I converting enzyme inhibitior 2

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC23H36N6O8

DescriptionStandard

        GPPGPT
    

Molecular Weight524.57 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0400

GRAVY Index-1.05

Hydrophobic Moment 0.13

Boman Index0.21

Instability Index40.43

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 202.68

LogP -3.02

H-bond Donors 5.0

H-bond Acceptors 8.0

Rotatable Bonds 9.0

Heavy Atoms 37.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0142129 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyAngiotensin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity88 μM

MethodIC50

RECORD: Rec_0157948 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antidiabetic DPP-IV inhibitory

TargetDipeptidyl peptidase IV