Peptide Database

Peptide NameSAPTEFERN-amide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC44H67N13O17

DescriptionStandard

        SAPTEFERN
    

Molecular Weight1050.08 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-1.53

Net Charge (pH 7.4) -1.74

Charge Density (pH 7.0) -0.1705

GRAVY Index-1.50

Hydrophobic Moment 0.49

Boman Index-0.34

Instability Index65.40

Aliphatic Index 11.11

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 507.38

LogP -6.71

H-bond Donors 17.0

H-bond Acceptors 16.0

Rotatable Bonds 32.0

Heavy Atoms 74.0

Ring Count 2.0

Amide Bonds 9.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0082161 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila virilis [Animal]

FamilyFMRFamide related peptide

Tax ID7244

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0113730 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0233370 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0351248 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila virilis [Animal]

FamilySAPTEFERN-amide

Tax ID7244

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour