Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC376H584N104O106S11

DescriptionStandard

        MAKFASIVPMLFVVLVVFAALETPTMVEARLCERSSGTWSGVCGNNNACKGQCQRLEGAQHGSCNYVFPAHKCICYFNC
    

Molecular Weight8610.01 Da

Isoelectric Point (pI)8.16

Net Charge (pH 7.0)1.60

Net Charge (pH 7.4) 1.15

Charge Density (pH 7.0) 0.0203

GRAVY Index0.32

Hydrophobic Moment 0.51

Boman Index0.17

Instability Index26.54

Aliphatic Index 74.05

Aromaticity 0.1013

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3339.88

LogP -34.37

H-bond Donors 122.0

H-bond Acceptors 121.0

Rotatable Bonds 276.0

Heavy Atoms 597.0

Ring Count 14.0

Amide Bonds 86.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0343267 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence