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MYP_063588
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Basic Information
Siamycin II
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV
Standard
21 amino acids
C98H139N23O27S4
Standard
Sequence
CLGIGSCNDFAGCGYAIVCFW
Physicochemical Analysis
2199.55 Da
4.05
-1.28
-1.54
-0.0609
1.17
0.30
0.51
29.78
79.05
0.1905
6990.00
7240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
781.96
-6.33
31.0
30.0
65.0
152.0
5.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004622 VERIFIED: YES
Provenance & Taxonomy
Streptomyces strain AA6532 [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Pseudomonas aeruginosa A9843A
100 μg/mL
MIC
PMID8557614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8557614/
RECORD: Rec_0044375 VERIFIED: NO
Provenance & Taxonomy
Bacteria [Bacterium]
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0067951 VERIFIED: YES
Provenance & Taxonomy
Streptomyces strain AA6532 [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus A15036
3.1 μg/mL
MIC
PMID8557614 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8557614/
RECORD: Rec_0092812 VERIFIED: YES
Provenance & Taxonomy
Streptomyces strains AA3891 [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID7787424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7787424/
RECORD: Rec_0102659 VERIFIED: NO
Provenance & Taxonomy
Streptomyces strains [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
PaperHigh-resolution solution structure of siamycin II: novel amphipathic character of a 21-residue peptide that inhibits HIV fusion.
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