Peptide Database

Peptide NameMacrophage migration inhibitory factor

Function Ontology

Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC548H857N151O162S6

DescriptionStandard

        PMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
    

Molecular Weight12344.97 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)1.11

Net Charge (pH 7.4) 0.89

Charge Density (pH 7.0) 0.0097

GRAVY Index-0.02

Hydrophobic Moment 0.56

Boman Index0.12

Instability Index30.56

Aliphatic Index 88.16

Aromaticity 0.0877

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4985.54

LogP -53.26

H-bond Donors 172.0

H-bond Acceptors 171.0

Rotatable Bonds 395.0

Heavy Atoms 867.0

Ring Count 21.0

Amide Bonds 127.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0150572 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMIF family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods77-Lys: N6-acetyllysine; alternate; 77-Lys: N6-succinyllysine; alternate

Bio-Activity Profile

Function

Cytokine Growth factor MIF family Chemoattractant Chemokine-like