Peptide Database

Peptide NameNeutrophil defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC470H746N128O134S8

DescriptionStandard

        MRTLVILAAILLVALQAQAEPLQARTDEATAAQEQIPADNPEVVISFAWDESLAPKDSVPGLRKNMACYCRIPVCLAGERRYGTCFYLGRVWAFCC
    

Molecular Weight10590.25 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0161

GRAVY Index0.24

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index52.33

Aliphatic Index 97.71

Aromaticity 0.0833

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4168.93

LogP -35.53

H-bond Donors 149.0

H-bond Acceptors 141.0

Rotatable Bonds 338.0

Heavy Atoms 740.0

Ring Count 16.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377206 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus roxellana [Bacterium]

FamilyDefensin

Tax ID61622

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Antibiotic Defensin Non-hemolytic Non-ribosomal