Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC422H686N104O109S

DescriptionStandard

        MEKLKKLGLSSLFLIAGVIVFSQLPQIDLASTFGISGYAAKKIIDIAAGAGSVFAIIAVVGGTAGWGAILLAAAKALLKKYGRAAAASW
    

Molecular Weight8992.66 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.26

Charge Density (pH 7.0) 0.0617

GRAVY Index0.95

Hydrophobic Moment 0.61

Boman Index0.40

Instability Index13.96

Aliphatic Index 129.66

Aromaticity 0.0899

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3337.58

LogP -23.44

H-bond Donors 118.0

H-bond Acceptors 116.0

Rotatable Bonds 300.0

Heavy Atoms 636.0

Ring Count 11.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060614 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus termiticola [Virus]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal