Peptide Database

Peptide NameDarbepoetin alfa

Function Ontology

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Standard StatusStandard

Sequence Length193 amino acids

Chemical FormulaC947H1537N263O276S7

DescriptionStandard

        MGVHECPAWLWLLLSLLSLPLGLPVLGAPPRLICDSRVLERYLLEAKEAENITTGCNETCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQVNETLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTGEACRTGDR
    

Molecular Weight21247.39 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.66

Net Charge (pH 7.4) 1.22

Charge Density (pH 7.0) 0.0086

GRAVY Index0.03

Hydrophobic Moment 0.86

Boman Index0.06

Instability Index40.50

Aliphatic Index 107.67

Aromaticity 0.0622

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28210.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8646.51

LogP -104.92

H-bond Donors 306.0

H-bond Acceptors 287.0

Rotatable Bonds 702.0

Heavy Atoms 1493.0

Ring Count 27.0

Amide Bonds 207.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405259 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Chinese hamster ovary cell line [Animal]

FamilyGrowth factor

Tax ID9606; 10029

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGlycosylation

Bio-Activity Profile

Function

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TargetCHO