Peptide Database

Peptide NameTeixobactin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC51H85N11O15

DescriptionStandard

        FISQIISTAI
    

Molecular Weight1092.29 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0240

GRAVY Index1.68

Hydrophobic Moment 0.47

Boman Index0.61

Instability Index28.26

Aliphatic Index 166.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 429.00

LogP -3.16

H-bond Donors 15.0

H-bond Acceptors 15.0

Rotatable Bonds 35.0

Heavy Atoms 77.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071051 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic designed peptide

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralityall-D amino-acid peptide [D]

N-TermNone

C-TermNone

Other Modsadenylation, C, condensation; MT, methylation (of phenylalanine); T, thiolation (carrier); and TE,thioesterase (Ile-Thr ring closure). NmPhe,N-methylated phenylalanin

Bio-Activity Profile

Function

Antimicrobial Antimycobacterial

TargetMycobacterium tuberculosis H37Rv

MethodMIC