Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length174 amino acids

Chemical FormulaC828H1322N244O264S

DescriptionStandard

        VPASIPVVDAKPTTHPGVFSVSVPGLPDLQVSTVKNAPAMTALPRGVTDEKDRTVHPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKF
    

Molecular Weight18950.90 Da

Isoelectric Point (pI)5.85

Net Charge (pH 7.0)-2.88

Net Charge (pH 7.4) -3.34

Charge Density (pH 7.0) -0.0165

GRAVY Index-0.60

Hydrophobic Moment 0.62

Boman Index-0.10

Instability Index41.73

Aliphatic Index 72.30

Aromaticity 0.0517

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8191.07

LogP -94.98

H-bond Donors 275.0

H-bond Acceptors 266.0

Rotatable Bonds 623.0

Heavy Atoms 1337.0

Ring Count 27.0

Amide Bonds 190.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0021554 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli