Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC524H861N147O147S8

DescriptionStandard

        MKLILIIAILLFQKSKVTEQLKRCWSEYIRGYCRKICRISEIREVLCENGRYCCLNIVELEARRKITKPPPPKPRTYAMTFPQDDDIIVENYSRSKTNST
    

Molecular Weight11828.86 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)7.45

Net Charge (pH 7.4) 7.11

Charge Density (pH 7.0) 0.0745

GRAVY Index-0.39

Hydrophobic Moment 0.88

Boman Index-0.14

Instability Index47.74

Aliphatic Index 92.60

Aromaticity 0.0800

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4816.29

LogP -40.99

H-bond Donors 176.0

H-bond Acceptors 163.0

Rotatable Bonds 400.0

Heavy Atoms 826.0

Ring Count 15.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167206 VERIFIED: NO

Provenance & Taxonomy

OrganismVulpes vulpes [Bacterium]

FamilyDefensin

Tax ID9627

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence