Peptide Database

Peptide NameP11(derived from E2 envelope protein of GB virus C)

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC85H136N24O28S2

DescriptionStandard

        TGEKVWDRGNVTLLCDCP
    

Molecular Weight2006.26 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-1.62

Net Charge (pH 7.4) -1.84

Charge Density (pH 7.0) -0.0899

GRAVY Index-0.34

Hydrophobic Moment 0.45

Boman Index-0.04

Instability Index-1.12

Aliphatic Index 75.56

Aromaticity 0.0556

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 848.39

LogP -8.76

H-bond Donors 31.0

H-bond Acceptors 29.0

Rotatable Bonds 63.0

Heavy Atoms 139.0

Ring Count 3.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367568 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targetinhibition of HIV(HXB2) infection in TZM-bl Cells

Activity162.1 μM

MethodIC50

RECORD: Rec_0420933 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin