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MYP_063321
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Basic Information
Angiotensin-4
Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted protein
Cardiovascular
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Enzyme modulation ▸ Enzyme inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Reproductive biology ▸ Reproductive modulation
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
6 amino acids
C40H54N8O8
Standard
Sequence
VYIHPF
Physicochemical Analysis
774.91 Da
6.71
-0.18
-0.44
-0.0300
0.90
0.27
0.60
43.63
113.33
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
248.94
1.19
8.0
9.0
19.0
56.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0266247 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
ACE-inhibitory peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAngiotensin II and its heptapeptide (2-8), hexapeptide (3-8), and pentapeptide (4-8) metabolites in arterial and venous blood of man. PMID975455 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/975455/
RECORD: Rec_0305886 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Serpin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID21476495 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21476495/
RECORD: Rec_0360678 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Serpin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID3081342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3081342/
RECORD: Rec_0375929 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Angiotensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular Growth regulation Development regulation Receptor modulation
Mammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0425292 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Bos taurus [Animal]
9606; 9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PMID975455 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/975455/
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