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MYP_063306
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Basic Information
PhD1 (PhD-1; Defensin-1; primates, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
33 amino acids
C167H282N62O37S6
Standard
Sequence
RRICRCRIGRCLGLEVYFGVCFLHGRLARRCCR
Physicochemical Analysis
3942.81 Da
10.60
7.79
7.45
0.2360
0.15
0.80
-0.24
44.82
91.52
0.0909
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1637.83
-14.74
70.0
52.0
132.0
272.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0260041 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID16978151 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16978151/
RECORD: Rec_0304757 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Listeria monocytogenes
1.3 μM
MIC
Paperalpha-Defensins from blood leukocytes of the monkey Papio hamadryas
RECORD: Rec_0340579 VERIFIED: NO
Provenance & Taxonomy
Papio hamadryas [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-31; 6-21; 11-32
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli and the, Listeria monocytogenes and, Staphylococcus aureus, Candida albicans
RECORD: Rec_0386827 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
>50 μM
MIC
Paperalpha-Defensins from blood leukocytes of the monkey Papio hamadryas
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