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MYP_063306
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Basic Information
PhD1 (PhD-1; Defensin-1; primates, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
33 amino acids
C167H282N62O37S6
Standard
Sequence
RRICRCRIGRCLGLEVYFGVCFLHGRLARRCCR
Physicochemical Analysis
3942.81 Da
10.60
7.79
7.45
0.2360
0.15
0.80
-0.24
44.82
91.52
0.0909
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1637.83
-14.74
70.0
52.0
132.0
272.0
4.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0177324 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Alpha-defensin; Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Listeria monocytogenes
PMID16978151 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16978151/
RECORD: Rec_0192866 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID16978151 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16978151/
RECORD: Rec_0209319 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 57.6%, T 18.2%, C 24.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0210068 VERIFIED: YES
Provenance & Taxonomy
Papio hamadryas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
3.8 μM
MIC
Paperalpha-Defensins from blood leukocytes of the monkey Papio hamadryas
RECORD: Rec_0226723 VERIFIED: YES
Provenance & Taxonomy
Hamadryas baboon [Animal]; Mammalia [Animal]
33208; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
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